The combined continuous administration of progestin and estrogen reduces the risk of which cancer?

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Terms in this set (10)

D

Alendronate can cause erosive esophagitis. To prevent this adverse effect, it is important for the patient to take the medication with an 8-oz glass of water in the morning on an empty stomach without any other medications and maintain an upright position for 30 minutes. These actions facilitate rapid absorption and prevent reflux into the esophagus.

Which statement by the patient indicates an understanding of discharge teaching for the medication alendronate (Fosamax)?

"I need to decrease my intake of dairy products to prevent hypercalcemia."
"This medication will help relieve the bone pain I have from my osteoporosis."
"I need to take this medication with food to prevent damage to my esophagus caused by reflux of stomach acid."
"I will take the medication in the morning before I eat with 8 oz of water and remain upright for 30 minutes."

D

Estrogen, given alone, has been associated with an increased risk of endometrial hyperplasia, which can lead to endometrial cancer. Progestin reduces the incidence of endometrial hyperplasia.

The combined continuous administration of progestin and estrogen reduces the risk of which cancer?
Breast
Vaginal
Ovarian
Endometrial

D

The nurse would question a prescription for estrogen replacement therapy in a patient with a history of which condition?
Weight loss
Dysmenorrhea
Vaginal bleeding
Deep vein thrombosis

A

During a postpartum patient assessment, the nurse notes a boggy uterus and increased vaginal bleeding. Based on this assessment data, the nurse prepares to administer which medication?
Oxytocin (Pitocin)
Clomiphene (Clomid)
Terbutaline (Brethine)
Dinoprostone (Prostin E2)

B

Which laboratory test would the nurse expect the health care provider to prescribe to monitor a patient for adverse effects related to progestin medications?
Cardiac enzymes
Liver function tests
Complete blood count
Serum creatinine level

C

A female patient arrives to the clinic for counseling on potential hormone replacement therapy. When taking the patient's history, which condition would the nurse consider as a contraindication to use of hormone replacement therapy for the patient?
Osteoporosis
Hyperlipidemia
Thromboembolic events
Early onset of menarche

C

When educating a patient about the use of oral contraceptives, the nurse provides what explanation for the pills having different colors each week?
"They help you remember which week you are taking."
"There isn't a reason for the color; it's just the choice of the drug company."
"The different color pills are because of different amounts of hormones in each week."
"They are color coded for the weeks of the month."

C

A patient taking oral contraceptives is being treated for a urinary tract infection with antibiotics. Which information should the nurse include as education related to the oral contraceptives?
"Report any abdominal pain, blood in the urine, or changes in vision."
"There is no drug interaction between oral contraceptives and antibiotics."
"Use an alternative method of birth control for up to 1 month during and after antibiotic use."
"Your sexual partner should use a nonprescription test kit that will detect a urinary tract infection."

C

An elderly female patient being treated for osteoporosis with a selective estrogen receptor modulator (SERM) should alert the nurse for an increased risk of which condition?
Hypertension
Hypercalcemia
Deep vein thrombosis
Coronary heart disease

A

What is the most common drug used for induction of labor in pregnant women and to promote ejection of milk during lactation?
Oxytocin (Pitocin)
Clomiphene (Clomid)
Misoprostol (Cytotec)
Mifepristone (Mifeprex)

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What is the purpose of giving estrogen therapy in combination with progestin?

Combinations of estrogen and progestin work by preventing ovulation (the release of eggs from the ovaries). They also change the lining of the uterus (womb) to prevent pregnancy from developing and change the mucus at the cervix (opening of the uterus) to prevent sperm (male reproductive cells) from entering.

Does progestin decrease risk of breast cancer?

Some synthetic progestins, when added to oestrogen in HRT for menopausal symptoms, have been reported to increase the risk of breast cancer more than oestrogen alone. Progestin use in breast cancer survivors is associated with an increased breast cancer risk compared with its non-use [4].

Does estrogen prevent endometrial cancer?

Women who take progesterone along with estrogen to treat menopausal symptoms do not have an increased risk of endometrial cancer. Still, taking this combination increases a woman's chance of developing breast cancer and also increases the risk of serious blood clots.

Does progestin increase risk of breast cancer?

Unlike studies of other oral contraceptives, studies indicate that progestin-only formulations do not increase the risk of breast cancer, although the literature is hampered by small sample sizes.

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