Which form of nitroglycerin is likely to have a large first-pass effect Quizlet

Aspirin-

Morphine-

Beta-blockers-

Nitroglycerine-

Nonsteroidal antiinflammatory drugs (NSAIDs)

Drugs used to immediately address STEMI before a definitive diagnosis include aspirin to produce an immediate antiplatelet effect; morphine to treat STEMI-associated pain; beta-blockers to reduce cardiac pain, infarct size, and short-term mortality; and nitroglycerin to reduce preload and thereby oxygen demand, increase collateral blood flow in the ischemic region of the heart, control hypertension caused by anxiety, limit infarct size, and improve left ventricular function. NSAIDs should not be used since they can increase the risk of mortality, reinfarction, hypertension, heart failure, and myocardial rupture.

Have the patient swallow the pill, because it cannot be crushed.

Call the health care provider about an alternative form of nitrate for administration.-

Place the nitrate under the patient's tongue and let it dissolve, because the person has dysphagia.

Crush the isosorbide mononitrate into a fine powder, dilute it with water, and administer it via the enteral tube.

The nurse should contact the prescriber for an alternaive form of nitrate, such as a non-sustained-release pill, transdermal patch, topical ointment, or immediate release. Because isosorbide mononitrate is a sustained-release pill, it cannot be crushed. Because the patient has dysphagia, attempting to administer the pill orally could result in aspiration. Sustained-release tablets must be administered whole.

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Which side effect is associated with the use of Nitroglycerin?

Headache, dizziness, lightheadedness, nausea, flushing, and burning/tingling under the tongue may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Which of the following administration route for Nitroglycerin is the most common?

There are intravenous (IV) routes of administration for nitroglycerin used most commonly in emergency rooms and intensive care units (ICU).

What is Nitroglycerin used for quizlet?

Use Nitroglycerin for Acute Angina Pectoris, Ischemia Chest Pain, Hypertension, CHF, and Pulmonary Edema.

What is isosorbide mononitrate?

Isosorbide mononitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.

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