What is a Systematic Review?A systematic review is a type of publication that addresses a clinical question by analyzing research that fits certain explicitly-specified criteria. The criteria for inclusion is usually based on research from clinical trials and observational studies. Assessments are done based on stringent guidelines, and the reviews are regularly updated. These are usually considered one of the highest levels of evidence and usually address diagnosis and treatment questions. Show
Benefits of Systematic Reviews Systematic reviews refine and reduce large amounts of data and information into one document, effectively summarizing the evidence to support clinical decisions. Since they are typically undertaken by a entire team of experts, they can take months or even years to complete, and must be regularly updated. The teams are usually comprised of content experts, an experienced searcher, a bio-statistician, and a methodologist. The team develops a rigorous protocol to thoroughly locate, identify, extract, and analyze all of the evidence available that addresses their specific clinical question. As systematic reviews become more frequently published, concern over quality led to the PRISMA Statement to establish a minimum set of items for reporting in systematic reviews and meta-analyses. Many systematic reviews also contain a meta-analysis. What is a Meta-Analysis?Meta-analysis is a particular type of systematic review that focuses on selecting and reviewing quantitative research. Researchers conducting a meta-analysis combine the results of several independent studies and reviews to produce a synthesis where possible. These publications aim to assist in making decisions about a particular therapy. Benefits of Meta-Analysis A meta-analysis synthesizes large amounts of data using a statistical examination. This type of analysis provides for some control between studies and generalized application to the population. To learn how to find systematic reviews in the Walden Library, please see the Levels of Evidence Pyramid page: Evidence-based practice is a conscientious, problem-solving approach to clinical practice that incorporates the best evidence from well-designed studies, patient values and preferences, and a
clinician's expertise in making decisions about a patient's care. Unfortunately, no standard formula exists for how much these factors should be weighed in the clinical decision-making process. However, there are a variety of rating systems and hierarchies of evidence that grade the strength or quality of evidence generated from a research study or report. Being knowledgeable about evidence-based practice and levels of evidence is important to every clinician as clinicians need to be confident
about how much emphasis they should place on a study, report, practice alert or clinical practice guideline when making decisions about a patient's care. The levels of evidence listed here have been developed with the help of nurse experts and other industry resources. We thank those who have contributed to making our system relevant and applicable to determining the levels of evidence that support our CE publications. Evidence-based information ranges from
Level A (the strongest) to Level C (the weakest). In 2013, Level ML, multilevel, was added to identify clinical practice guidelines that contain recommendations based on more than one level of evidence: Evidence-based Practice Resources:
References for EBP:Alfaro-LeFevre R. Critical Thinking, Clinical Reasoning, and Clinical Judgment: A Practical Approach. 5th ed. St. Louis, MO: Elsevier-Saunders; 2013. Ebell MH, Siwek J, Weiss BD, et al. Strength of recommendation taxonomy (SORT): a patient centered approach to grading evidence in the medical literature. Am Fam Physician. 2004;69(3):548-556. http://www.aafp.org/afp/2004/0201/p548.html. Published February 1, 2004. Accessed November 11, 2015. Evidence-based medicine toolkit. American Academy of Family Physician Web site. http://www.aafp.org/journals/afp/authors/ebm-toolkit.html. Accessed November 11, 2015. What is evidence based medicine? University of Illinois at Chicago University Library Web site. http://researchguides.uic.edu/ebm. Updated March 7, 2008. Accessed November 11, 2015. Levels of evidence. Oxford Centre for Evidence-Based Medicine Web site. http://www.cebm.net/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/. Published March 2009. Updated April 15, 2011. Accessed November 11, 2015. Melnyk BM, Fineout-Overholt E. Evidence-Based Practice in Nursing & Healthcare. A Guide to Best Practice. Philadelphia, PA: Lippincott Williams & Wilkins; 2005. Newhouse RP, Dearholt SL, Poe SS, Pugh LC, White KM. Johns Hopkins Nursing Evidence-Based Practice Model and Guidelines. Indianapolis, IN: Sigma Theta Tau International; 2007. Strength of recommendation taxonomy (SORT). American Academy of Family Physicians Web site. http://www.aafp.org/dam/AAFP/documents/journals/afp/sortdef07.pdf. Accessed November 11, 2015. Understanding research study designs. University of Minnesota Bio-Medical Library Web site. http://www.biomed.lib.umn.edu/guides/understanding-research-study-designs. Accessed November 11, 2015. What provides the strongest evidence on which to base clinical practice?The systematic review or meta-analysis of randomized controlled trials (RCTs) and evidence-based practice guidelines are considered to be the strongest level of evidence on which to guide practice decisions.
What provides the strongest evidence on which to base clinical practice quizlet?Along with systematic reviews or meta-analyses, randomized controlled studies provide the strongest evidence on which to base clinical practice.
Which is considered the highest quality evidence quizlet?Which is considered the highest quality evidence? A systematic review or meta-analysis of an RCT is considered the highest level of quality evidence.
Which type of evidenceThe highest level of evidence consists of the systematic review (SR) and meta-analysis using two or more randomized controlled trials (RCTs) of human subjects.
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