Show Your Paper Your Way We now differentiate between the requirements for new and revised submissions. You may choose to submit your manuscript as a single Word or PDF file to be used in the refereeing
process. Only when your paper is at the revision stage, will you be requested to put your paper in to a 'correct format' for acceptance and provide the items required for the publication of your article. Types of Article Cancer Letters is an international journal that considers full length articles and Mini Reviews in the broad area of basic and translational oncology. Additionally, special issues highlight topical areas in cancer research. Areas of interest to the broad readership of Cancer Letters include the molecular genetics and cell biology of cancer, radiation biology, molecular pathology, hormones and cancer, viral oncology, metastasis, chemoprevention and targeted therapies for personalized cancer medicine. Noncoding RNA (ncRNA) and its role in different types of human cancer has been a highlight topic for Cancer Letters over the past years, manuscripts in this area are particularly welcome. Mini Reviews Cancer Letters operates a single blind review process. All original papers should be between 3000 and 3500 words and will be initially assessed by the Editors for suitability for the journal. Papers deemed suitable are then sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. More information on types of peer review. The Editorial Office has adopted a rating system, in order to establish which manuscripts will be sent out for peer review. The rating system allows the Editor to assess the manuscript in terms of the following criteria: * Presentation Those manuscripts which are judged as being eligible for consideration by the Editors will be subject to peer review. Prior Publication Page charges Submission Checklist Ensure that the following items are present: One author has been designated as the corresponding author with contact details: All
necessary files have been uploaded: Further considerations For further information, visit our Support Center.
 Ethics and Procedures The editors and publisher of this Journal believe that there are fundamental principles underlying scholarly or professional publishing. While
this may not amount to a formal "code of conduct", these fundamental principles with respect to the authors' paper are that the paper should: Of equal importance are ethical guidelines dealing with research methods and research funding, including issues dealing with informed consent, research subject privacy rights, conflicts of interest, and sources of funding. While it may not be possible to draft a "code" that applies adequately to all instances and circumstances, we believe it useful to outline our expectations of authors and procedures that the Journal will employ in the event of questions concerning author conduct. Relevant conflicts of interest should be disclosed (see https://www.elsevier.com/conflictsofinterest). Studies involving experiments with animals must state that their care was in accordance with institution guidelines. Authors should include a statement in the manuscript that informed consent was obtained for experimentation with human subjects. The privacy rights of human subjects must always be observed. All animal experiments should comply with the ARRIVE guidelines and should be carried out in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU
Directive 2010/63/EU for animal experiments, or the National Research Council's Guide for the Care and Use of Laboratory Animals and the authors should clearly indicate in the manuscript that such guidelines have been followed. The sex of animals must be indicated, and where appropriate, the influence (or association) of sex on the results of the study. Work on human beings that is submitted to Cancer Letters should comply with the principles laid down in the Declaration of Helsinki; Recommendations guiding physicians in biomedical research involving human subjects. Adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964, amended by the 29th World Medical Assembly, Tokyo, Japan, October 1975, the 35th World Medical Assembly, Venice, Italy, October 1983, and the 41st World Medical Assembly, Hong Kong, September 1989. The manuscript should contain a statement that the work has been approved by the appropriate ethical committees related to the institution(s) in which it was performed and that subjects gave informed consent to the work. Studies involving experiments with animals must state that their care was in accordance with institution guidelines. Patients' and volunteers' names, initials, and hospital numbers should not be used. Guidelines for Formatting Gene and
Protein Names Reliability of results based on cultivated animal and human cells Informed consent and patient details Studies on patients or volunteers require ethics committee approval and informed consent, which should be documented in the paper. Appropriate consents, permissions and releases must be obtained where an author wishes to include case details or other personal information or images of patients and any other individuals in an Elsevier publication. Written consents must be retained by the author but copies should not be provided to the journal. Only if specifically requested by the journal in exceptional circumstances (for example if a legal issue arises) the author must provide copies of the consents or evidence that such consents have been obtained. For more information, please review the Elsevier Policy on the Use of Images or Personal Information of Patients or other Individuals. Unless you have written permission from the patient (or, where applicable, the next of kin), the personal details of any patient included in any part of the article and in any supplementary materials (including all illustrations and videos) must be removed before submission. Declaration of competing interest Corresponding authors, on behalf of all the authors of a submission, must disclose any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding. All authors, including those without competing interests to declare, should provide the relevant information to the corresponding author (which, where relevant, may specify they have nothing to declare). Corresponding authors should then use this tool to create a shared statement and upload to the submission system at the Attach Files step. Please do not convert the .docx template to another file type. Author signatures are not required. Submission of Manuscripts Manuscripts should be submitted online at https://www.editorialmanager.com/CANLET/default.aspx and the instructions on the site should be closely followed. Authors may submit manuscripts and track their progress through to final decision. Authors unable to submit online should contact the Editorial Office: Cancer Letters Editorial Office Submission of an article to Cancer Letters implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or any other language, without the written consent of the Publisher. Manuscripts should be submitted in English. Authors' full names, academic or professional affiliations, and addresses should be included on the first page. All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or the acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted. The name, postal address, email address and phone number of the corresponding author should be provided. Authors should supply the names, institutional mailing address and institutional email addresses of 5 potential reviewers for their manuscript and indicate why each reviewer would be competent for reviewing the manuscript. To provide an international perspective, no more than 2 potential reviewers should be from the same country. Please do not suggest reviewers from your own institution, previous or current collaborators or Editorial Board members. Please do not contact any reviewers that you have suggested. Without reviewer suggestions, processing of the manuscript may be delayed. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used. For more details, visit our Support site. Online submission guidelines can be followed at https://www.editorialmanager.com/CANLET/default.aspx. Via this website you will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files into a single Adobe Acrobat PDF version of the article, which is used in the peer review process. Please note that although manuscript source files are converted to PDF at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by email and via the author's homepage, removing the need for a hard-copy paper trail. Submission declaration and verification Submission of an article implies that the work described has not been published previously (except in the form of an abstract, a published lecture or academic thesis, see 'Multiple, redundant or concurrent publication' for more information), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify compliance, your article may be checked by Crossref Similarity Check and other originality or duplicate checking software. Preprints Use of inclusive language Inclusive language acknowledges diversity, conveys respect to all people, is sensitive to differences, and promotes equal opportunities. Content should make no assumptions about the beliefs or commitments of any reader; contain nothing which might imply that one individual is superior to another on the grounds of age, gender, race, ethnicity, culture, sexual orientation, disability or health condition; and use inclusive language throughout. Authors should ensure that writing is free from bias, stereotypes, slang, reference to dominant culture and/or cultural assumptions. We advise to seek gender neutrality by using plural nouns ("clinicians, patients/clients") as default/wherever possible to avoid using "he, she," or "he/she." We recommend avoiding the use of descriptors that refer to personal attributes such as age, gender, race, ethnicity, culture, sexual orientation, disability or health condition unless they are relevant and valid. When coding terminology is used, we recommend to avoid offensive or exclusionary terms such as "master", "slave", "blacklist" and "whitelist". We suggest using alternatives that are more appropriate and (self-) explanatory such as "primary", "secondary", "blocklist" and "allowlist". These guidelines are meant as a point of reference to help identify appropriate language but are by no means exhaustive or definitive. Author contributions For transparency, we encourage authors to submit an author statement file outlining their individual contributions to the paper using the relevant CRediT roles: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administration; Resources; Software; Supervision; Validation; Visualization; Roles/Writing - original draft; Writing - review & editing. Authorship statements should be formatted with the names of authors first and CRediT role(s) following. More details and an example. Article transfer service Copyright Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (see more information on this). An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement. Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations. If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases. For gold open access articles: Upon acceptance of an article, authors will be asked to complete a 'License Agreement' (more information). Permitted third party reuse of gold open access articles is determined by the author's choice of user license. Author rights Elsevier supports responsible sharing Role of the funding source You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement, it is recommended to state this. Elsevier Researcher
Academy Language (usage and editing services) Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop https://webshop.elsevier.com/language-editing-services/language-editing/ or visit our customer support site https://service.elsevier.com for more information. Authors should be aware that papers written in poor English are more likely to be rejected. Submission Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail. Submit your article
Reviewer Suggestions Authors should supply the names and institutional email addresses of 5 potential reviewers for their manuscript and indicate why each reviewer would be competent for reviewing the manuscript. To provide an international perspective, no more than 2 potential reviewers should be from the same country. Please do not suggest reviewers from your own institution, previous or current collaborators or Editorial Board members. Please do not contact any reviewers that you have suggested. Without reviewer suggestions, processing of the manuscript may be delayed. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used. For more details, visit our Support site.
Preparation of Manuscript Please strive for a professionally prepared manuscript of high technical and scientific quality. Many reviewers are overwhelmed with review requests. Our experience is that they are more likely to agree to review a well prepared manuscript. Articles should be submitted in the following order : Title, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgements, References. Please number the headings in your manuscript as follows: Title must address the main result of the study and preferably not exceed 185 characters, including spaces. Extraneous words such as 'study' 'investigation', 'analysis', etc, should be avoided. Acknowledgements. All contributors who do not meet the criteria for authorship as defined above should be listed in an acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a departmental chair who provided only general support. Authors should disclose whether they had any writing assistance and identify the entity that paid for that assistance. Cover Letter Manuscript submissions must be accompanied by a cover letter on institute letterhead with complete institute or laboratory coordinates: Official institute/laboratory name at research institution/university, full postal address, with phone and official institute/laboratory email of corresponding author. Personal email, both on cover letter and also on manuscript, will not be accepted. Academic role of corresponding author at the institution must be identified (Professor, Associate/Assistant Professor; Head of Laboratory). The cover letter should outline the significance of the results in no more than 5 sentences. Only submissions following these requests will be considered. NEW SUBMISSIONS Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts your files to a single PDF file, which is used in the peer-review process. References Formatting requirements Figures and tables embedded in text REVISED SUBMISSIONS Use of word processing software Essential title page information • Title. Concise and
informative. Titles are often used in information-retrieval systems and careful thought should be given to them. Titles should be informative, they should present the main result(s), best will be to design the title as a take-home message. Avoid abbreviations and formulae where possible and avoid addressing simply what you have done, such as "Profiling of?.", "Analysis of?.", also "Effect of."., "Role of."., "Correlation of.", "Association of.", "Modulation of.", or titles with a question mark.
Note: If there is more than one corresponding author, please mention the main corresponding author and followed by additional corresponding authors in the Title page Twitter handle. If you would like your Twitter handle to be included on your published paper, please provide it on your title page. Highlights Highlights are mandatory for this journal as they help increase the discoverability of your article via search engines. They consist of a short collection of bullet points that capture the novel results of your research as well as new methods that were used during the study (if any). Please have a look at the examples here: example Highlights. Highlights should be submitted in a separate editable file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point). Abstract A concise and factual abstract is required not exceeding 185 words. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself. Keywords Immediately after the abstract, provide a maximum of 5 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes, therefore please try to avoid duplicating words which have already appeared in the title of the paper. Abbreviations
Acknowledgements Formatting of funding sources Funding: This work was supported by the National Institutes of Health [grant numbers xxxx, yyyy]; the Bill & Melinda Gates Foundation, Seattle, WA [grant number zzzz]; and the United States Institutes of Peace [grant number aaaa]. It is not necessary to include detailed descriptions on the program or type of grants and awards. When funding is from a block grant or other resources available to a university, college, or other research institution, submit the name of the institute or organization that provided the funding. If no funding has been provided for the research, it is recommended to include the following sentence: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Footnotes Artwork Electronic artwork A detailed guide on electronic artwork is
available. Color artwork Figure captions Tables Tables should be typed, with double spacing, each on a separate sheet, numbered consecutively with Roman numerals, and should only contain horizontal lines. A short descriptive heading should be given above each table, and any footnotes and explanations underneath. Data references Preprint references Reference management software
Reference formatting Journal abbreviations source Video Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include links to these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the file in one of our recommended file formats with a preferred maximum size of 150 MB per file, 1 GB in total. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content. Data visualization Include interactive data visualizations in your publication and let your readers interact and engage more closely with your research. Follow the instructions here to find out about available data visualization options and how to include them with your article. Supplementary material Supplementary material such as applications, images and sound clips, can be published with your article to enhance it. Submitted
supplementary items are published exactly as they are received (Excel or PowerPoint files will appear as such online). Please submit your material together with the article and supply a concise, descriptive caption for each supplementary file. If you wish to make changes to supplementary material during any stage of the process, please make sure to provide an updated file. Do not annotate any corrections on a previous version. Please switch off the 'Track Changes' option in Microsoft Office
files as these will appear in the published version. Research data This journal encourages and enables you to share data that supports your research publication where appropriate, and enables you to interlink the data with your published articles. Research data refers to the results of observations or experimentation that validate research findings. To facilitate reproducibility and data reuse, this journal also encourages you to share your software, code, models, algorithms, protocols, methods and other useful materials related to the project. Below are a number of ways in which you can associate data with your article or make a statement about the availability of your data when submitting your manuscript. If you are sharing data in one of these ways, you are encouraged to cite the data in your manuscript and reference list. Please refer to the "References" section for more information about data citation. For more information on depositing, sharing and using research data and other relevant research materials, visit the research data page. Data linking There are different ways to link your datasets to your article. When available, you can directly link your dataset to your article by providing the relevant information in the submission system. For more information, visit the database linking page. For supported data repositories a repository banner will automatically appear next to your published article on ScienceDirect. In addition, you can link to relevant data or entities through identifiers within the text of your manuscript, using the following format: Database: xxxx (e.g., TAIR: AT1G01020; CCDC: 734053; PDB: 1XFN). Research Elements This journal enables you to publish research objects related to your original research – such as data, methods, protocols, software and hardware – as an additional paper in Research Elements. Research Elements is a suite of peer-reviewed, open access journals which make your research objects findable, accessible and reusable. Articles place research objects into context by providing detailed descriptions of objects and their application, and linking to the associated original research articles. Research Elements articles can be prepared by you, or by one of your collaborators. During submission, you will be alerted to the opportunity to prepare and submit a Research Elements article. More information can be found on the Research Elements page. Data statement
Online proof correction To ensure a fast publication process of the article, we kindly ask authors to provide us with their proof corrections within two days. Corresponding authors will receive an e-mail with a link to our online proofing system, allowing annotation and correction of proofs online. The environment is similar to MS Word: in addition to editing text, you can also comment on figures/tables and answer questions from the Copy Editor. Web-based proofing provides a faster and
less error-prone process by allowing you to directly type your corrections, eliminating the potential introduction of errors. Offprints The corresponding author will, at no cost, receive a customized Share Link providing 50 days free access to the final published version of the article on ScienceDirect. The Share Link can be used for sharing the article via any communication channel, including email and social media. For an extra charge, paper offprints can be ordered via the offprint order form which is sent once the article is accepted for publication. Both corresponding and co-authors may order offprints at any time via Elsevier's Author Services. Corresponding authors who have published their article gold open access do not receive a Share Link as their final published version of the article is available open access on ScienceDirect and can be shared through the article DOI link. Which of the following is considered a good way to gain an audience's attention?Engage the audience — get them interested, give them a reason to listen.. Describe a scene or a character.. Tell a story.. Share a personal experience.. Relate to a recent event.. Piggyback on a previous speaker's remark or theme.. Point out something important about the audience or the current setting.. Which of the following are among the main principles of outlining?The principles of outlining include consistency, unity, coherence, and emphasis. Coordinate points in an outline are on the same level of importance in relation to the thesis of the speech or the central idea of a main point. Subordinate points provide evidence for a main idea or thesis.
Which of the following are among the main principles of outlining quizlet?Which of the following are among the main principles of outlining? 1- All items in your outline should be related to your purpose. 2- Each outline part is a single idea.. Narrow your topic.. Look for supporting materials.. Select an appropriate topic.. Why is it so important to select the appropriate outline format?Using a standard outline format, you can make decisions about your main points, the specific information you will use to support those points, and the language you will use. Without an outline, your message is liable to lose logical integrity.
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In which of the following ways is a complete sentence outline superior to a manuscript?
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